Sugi Predict

Sugi Predict / Compounds / Propachlor

Propachlor

Propachlor

SCHEMBL1701162

CC(C)N(C(=O)CCl)c1ccccc1.CC(C)N(C(=O)CCl)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 1.00
▸ LMNA P02545 5/20 1.00
▸ SMN1; SMN2 Q16637 4/20 1.00
▸ TP53 P04637 1/20 1.00
▸ KMT2A Q03164 6/20 0.58
▸ NPC1 O15118 5/20 0.58
▸ RAB9A P51151 5/20 0.58
▸ HTT P42858 4/20 0.58
▸ NPSR1 Q6W5P4 2/20 0.58
▸ POLB P06746 1/20 0.58
▸ PAX8 Q06710 4/20 0.50
▸ GLA P06280 1/20 0.50
▸ MAPT P10636 1/20 0.49
▸ MEN1 O00255 3/20 0.47
▸ MITF O75030 2/20 0.47
▸ JAK2 O60674 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ MLYCD O95822 2/20 0.46
▸ TRPM8 Q7Z2W7 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propachlor SCHEMBL65571 1.00 ALDH1A1 (1.00) ALDH1A1LMNASMN1; SMN2TP53KMT2A
Propachlor SCHEMBL27354235 0.87 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL11653644 0.86 ALDH1A1 (0.74) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL9869949 0.86 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL9869948 0.86 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2TP53KMT2A
Propachlor SCHEMBL8964243 0.85 ALDH1A1 (0.73) ALDH1A1LMNASMN1; SMN2TP53KMT2A
Toluene SCHEMBL29012444 0.85 ALDH1A1 (0.72) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL11382770 0.84 ALDH1A1 (0.73) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL22311444 0.84 ALDH1A1 (0.72) ALDH1A1LMNASMN1; SMN2TP53KMT2A
SCHEMBL9403533 0.83 ALDH1A1 (0.71) ALDH1A1LMNASMN1; SMN2TP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130210630-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (DE) 2013-08-15 — — US disclosed
WO-2012003441-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (US) 2012-01-05 — — WO disclosed
US-7019046-B2 Aqueous suspension agent for water insoluble compounds ISP INVESTMENTS INC. (US) 2006-03-28 — — US disclosed
US-20060039944-A1 Solid polymeric dispersant composition for water-insoluble actives ISP INVESTMENTS INC. 2006-02-23 — — US disclosed
US-20040024099-A1 Aqueous suspension agent for water insoluble compounds ISP INVESTMENTS INC. 2004-02-05 — — US disclosed
US-6303131-B1 CAN BE USED AS A COATING FOR SUBSTRATES, SUCH AS, WOOD, METAL, GLASS, ALSO ACTIVE INGREDIENT, E.G., FUNGICIDES, PRESERVATIVES, INSECTICIDES, INSECT REPELLENTS, PHEROMONES, RADIATION ABSORBENTS, DYES, CAN BE INCLUDED IN FORMULATION ISP INVESTMENTS INC. 2001-10-16 — — US disclosed
EP-0574492-B1 STABILIZATION OF MICROEMULSIONS USING HYDROPHOBIC ACID BUFFERS ISP INVESTMENTS INC (US) 1999-05-12 — — EP disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 — — EP disclosed
US-5766615-A MIXTURE CONTAINING LONG-CHAIN ALKYLPYRROLIDONE, ANIONIC SURFACTANT, GRAFT POLYMER OF N-VINYLPYRROLIDONE AND AN ALPHA-OLEFIN AND AN AGRICULTURALLY ACTIVE COMPOUND ISP INVESTMENTS INC. (US) 1998-06-16 — — US disclosed
WO-1998006780-A1 STABILIZER ADDITIVE FOR AGCHEMICAL TANK MIX ISP INVESTMENTS INC. (US) 1998-02-19 — — WO disclosed
US-5071463-A Stable, emulsifiable concentrate of an herbicide and pyrrolido ne derivative; dispersibility ISP INVESTMENTS INC. (US) 1991-12-10 — — US disclosed
EP-0457802-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-27 — — EP disclosed
WO-1991015478-A1 CROP-SELECTIVE HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 — — WO disclosed
WO-1991010653-A1 HERBICIDAL PYRIMIDINES AND TRIAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 — — WO disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 — — WO disclosed
WO-1991003464-A1 HERBICIDAL OXABICYCLO ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 — — WO disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 — — WO disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 — — WO disclosed
WO-1990009383-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-23 — — WO disclosed
WO-1990002130-A2 HERBICIDES FOR WEED CONTROL IN SUGAR BEETS, OILSEED RAPE AND COLE CROPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210630-A1 SELF-EMULSIFYING OIL PHOSPHO1, SQLE, ALOX15 ALDH1A1 3915/4885LMNA 936/4885SMN1; SMN2 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.