Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329775 | 0.83 | TSHR (0.46) | TP53ALDH1A1KDM4EHTTTSHR | |
| SCHEMBL1629818 | 0.79 | NQO1 (0.40) | NQO1GLAKMT2AALDH1A1MEN1 | |
| SCHEMBL9834426 | 0.78 | LMNA (0.39) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL15067112 | 0.75 | NQO1 (0.48) | NQO1TP53CYP3A4HSD17B10KMT2A | |
| SCHEMBL160560 | 0.73 | NQO1 (0.46) | NQO1TP53CYP3A4HSD17B10KMT2A | |
| SCHEMBL128388 | 0.73 | NQO1 (0.46) | NQO1TP53CYP3A4HSD17B10KMT2A | |
| SCHEMBL7772351 | 0.73 | NQO1 (0.46) | NQO1GLATP53CYP3A4HSD17B10 | |
| SCHEMBL1148347 | 0.72 | NQO1 (0.44) | NQO1TP53CYP3A4HSD17B10KMT2A | |
| SCHEMBL2078571 | 0.72 | NQO1 (0.44) | NQO1TP53CYP3A4HSD17B10KMT2A | |
| SCHEMBL456237 | 0.72 | CYP2A6 (0.42) | TP53HSD17B10KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115700-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AG (DE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017157-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |