Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725912 | 0.89 | NQO1 (0.40) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL721489 | 0.88 | NQO1 (0.43) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL1569511 | 0.88 | ESR1 (0.39) | NQO1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL20703535 | 0.87 | NQO1 (0.43) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL20703487 | 0.87 | NQO1 (0.43) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL20703590 | 0.86 | MAPK1 (0.42) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL15352587 | 0.83 | NQO1 (0.39) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL2772599 | 0.83 | MAOB (0.49) | CYP1A2LMNA | |
| SCHEMBL17205004 | 0.83 | PARP15 (0.37) | NQO1TP53CYP3A4 | |
| SCHEMBL15352665 | 0.82 | NQO1 (0.38) | NQO1TP53CYP3A4MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164641-A | Nickel complex for synthesizing polyketone resin, preparation method and application | 大连理工大学 | 2023-12-05 | — | — | CN | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | claimed |
| EP-3428202-A1 | PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2019-01-16 | — | — | EP | claimed |
| CN-105263969-B | Using metallocene polymerization catalyst preparation polyolefin and the method for copolymer | 埃克森美孚化学专利公司 | 2017-04-05 | — | — | CN | claimed |
| US-9611348-B2 | Process of producing polyolefins using metallocene polymerization catalysts and copolymers therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-04-04 | — | — | US | claimed |
| EP-3049419-A1 | NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT | China Medical University Hospital (TW) | 2016-08-03 | — | — | EP | claimed |
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | claimed |
| EP-2984111-A1 | PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2016-02-17 | — | — | EP | claimed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | claimed |
| EP-1546163-A1 | METHOD FOR THE PRODUCTION OF ACYLPHOSPHINE OXIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-29 | — | — | EP | claimed |
| WO-2004094439-A2 | METHOD FOR THE PRODUCTION OF ACYLPHOSPHINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-04 | — | — | WO | claimed |
| EP-1212331-B1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2004029063-A1 | METHOD FOR THE PRODUCTION OF ACYLPHOSPHINE OXIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-08 | — | — | WO | claimed |
| US-6649595-B2 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD GENE THERAPEUTICS, INC. | 2003-11-18 | — | — | US | claimed |
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD PHARMACEUTICALS, INC. | 2002-08-08 | — | — | US | claimed |
| EP-1212331-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001014387-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2001-03-01 | — | — | WO | claimed |
| US-6187757-B1 | Regulation of biological events using novel compounds | ARIAD PHARMACEUTICALS, INC. | 2001-02-13 | — | — | US | claimed |
| US-6015907-A | PHOTOSTABLE IMAGING DYES FOR ACID-MEDIATED MEDIA, ALSO FOR PHOTOSENSITIZING ONIUM SALTS TO VISIBLE BLUE RADIATION | POLAROID CORPORATION (US) | 2000-01-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | FKBP2, FKBP14, FKBP4 | NQO1 4587/4885TP53 415/4885CYP3A4 2404/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | NQO1 2074/4885TP53 3560/4885CYP3A4 4367/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | NQO1 2892/4885TP53 3242/4885CYP3A4 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.