Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768011 | 0.89 | LMNA (0.44) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL4607223 | 0.74 | LMNA (0.41) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL8377810 | 0.74 | LMNA (0.34) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL9186501 | 0.74 | CYP3A4 (0.35) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL8376814 | 0.74 | LMNA (0.34) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL7456031 | 0.73 | CYP1A2 (0.46) | CYP3A4CYP2C19LMNAALDH1A1PKM | |
| SCHEMBL17377719 | 0.72 | LMNA (0.45) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL11517863 | 0.71 | CYP3A4 (0.36) | CYP3A4CYP2C19CA12CA1CA9 | |
| SCHEMBL23886963 | 0.70 | CYP3A4 (0.59) | CYP3A4CYP2C19L3MBTL1LMNAALDH1A1 | |
| SCHEMBL9831013 | 0.69 | MEN1 (0.42) | CYP3A4CYP2C19CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546742-B1 | 4-(1,1-Dialkoxycarbonyl-alkyl)azetidin-2-one derivatives and synthesis of 4-(1-carboxy-alkyl)azetidin-2-one derivatives therefrom | TAKASAGO PERFUMERY CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |