Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959845 | 0.88 | LMNA (0.51) | MEN1KMT2AACELMNACA12 | |
| SCHEMBL951298 | 0.88 | LMNA (0.51) | MEN1KMT2AACELMNACA12 | |
| SCHEMBL3728882 | 0.86 | LMNA (0.46) | MEN1KMT2AACELMNACA12 | |
| SCHEMBL11187859 | 0.84 | LMNA (0.45) | MEN1KMT2AACELMNACA12 | |
| SCHEMBL28109752 | 0.84 | LMNA (0.45) | MEN1KMT2AACELMNACA12 | |
| SCHEMBL17377717 | 0.79 | KMT2A (0.40) | MEN1KMT2AACECSNK2A2CSNK2B | |
| SCHEMBL11517863 | 0.76 | CYP3A4 (0.36) | MEN1KMT2ALMNACA12CA1 | |
| SCHEMBL7068437 | 0.75 | LMNA (0.40) | MEN1KMT2ALMNACA12CA1 | |
| SCHEMBL5452977 | 0.75 | MEN1 (0.37) | MEN1KMT2AACECSNK2A2CSNK2B | |
| SCHEMBL15110370 | 0.75 | ALDH1A1 (0.39) | MEN1KMT2AACELMNACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |