Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548659 | 1.00 | CA2 (0.42) | CA2MAPK14CCNKCDK12ALDH1A1 | |
| SCHEMBL1075429 | 0.88 | MAPK14 (0.45) | MAPK14ALDH1A1 | |
| SCHEMBL1075428 | 0.88 | MAPK14 (0.45) | MAPK14ALDH1A1 | |
| SCHEMBL16193077 | 0.88 | MAPK14 (0.45) | MAPK14ALDH1A1 | |
| SCHEMBL9149708 | 0.87 | MAPT (0.50) | CA2MAPK14LMNA | |
| SCHEMBL7767530 | 0.87 | CA2 (0.43) | CA2MAPK14CCNKCDK12 | |
| SCHEMBL8662225 | 0.87 | CA2 (0.43) | CA2MAPK14CCNKCDK12 | |
| SCHEMBL1587316 | 0.84 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL1587319 | 0.84 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL7997698 | 0.82 | MAPK14 (0.44) | MAPK14CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |