Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587316 | 0.89 | MAPK14 (0.44) | MAPTSMN1; SMN2MAPK1MAPK14L3MBTL1 | |
| SCHEMBL1587319 | 0.89 | MAPK14 (0.44) | MAPTSMN1; SMN2MAPK1MAPK14L3MBTL1 | |
| SCHEMBL4012285 | 0.88 | L3MBTL1 (0.47) | MAPTSMN1; SMN2MAPK14L3MBTL1LMNA | |
| SCHEMBL1684530 | 0.87 | RAB9A (0.45) | MAPTRAB9ASMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL1684533 | 0.87 | RAB9A (0.45) | MAPTRAB9ASMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL7768491 | 0.87 | CA2 (0.42) | MAPK14LMNACA2 | |
| SCHEMBL27548659 | 0.87 | CA2 (0.42) | MAPK14LMNACA2 | |
| SCHEMBL1966013 | 0.87 | CA2 (0.43) | RAB9ASMN1; SMN2MAPK1CYP3A4MAPK14 | |
| SCHEMBL21197731 | 0.87 | CA2 (0.43) | RAB9ASMN1; SMN2MAPK1CYP3A4MAPK14 | |
| SCHEMBL1964361 | 0.87 | CA2 (0.43) | RAB9ASMN1; SMN2MAPK1CYP3A4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395910-A | Photostable polymers | AKZO NOBEL N.V. (NL) | 1995-03-07 | — | — | US | disclosed |
| EP-0550105-A2 | Liquid-crystalline polyurethanes, compositions of said liquid-crystalline polyurethanes, and a device for optical data storage comprising a liquid-crystalline polyurethane | Akzo Nobel N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |