Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926952 | 0.91 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL671910 | 0.90 | TSHR (0.41) | TSHRLMNATHRBALDH1A1 | |
| SCHEMBL7768610 | 0.88 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL19927009 | 0.85 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL21112921 | 0.83 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL21112842 | 0.81 | TSHR (0.40) | TSHRLMNATHRBALDH1A1 | |
| SCHEMBL9277808 | 0.79 | TSHR (0.37) | TSHRLMNATHRB | |
| SCHEMBL19926748 | 0.79 | — | — | |
| SCHEMBL7768613 | 0.79 | — | — | |
| SCHEMBL339790 | 0.78 | TSHR (0.35) | TSHRLMNATHRBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818903-B | Low-temperature-resistant long-chain hydrocarbon-organic silicon alternating copolymer and preparation method and application thereof | 杭州师范大学 | 2021-09-28 | — | — | CN | claimed |
| CN-110818903-A | Low-temperature-resistant long-chain hydrocarbon-organic silicon alternating copolymer and preparation method and application thereof | 杭州师范大学 | 2020-02-21 | — | — | CN | claimed |
| EP-3784718-B1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHERPOLYSILOXANE BLOCK COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20220411634-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | HENKEL AG & CO. KGAA (DE) | 2022-12-29 | — | — | US | disclosed |
| EP-4108726-A1 | SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY | Henkel AG & Co. KGaA (DE) | 2022-12-28 | — | — | EP | disclosed |
| US-11326027-B2 | Process for the preparation of hydroxyl-functionalized polysiloxanes | HENKEL AG & CO. KGAA (DE) | 2022-05-10 | — | — | US | disclosed |
| CN-114096590-A | UV and/or thermally curable silicone-based materials and formulations | 汉高知识产权控股有限责任公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-3953412-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | Henkel IP & Holding GmbH (DE) | 2022-02-16 | — | — | EP | disclosed |
| US-20220025180-A1 | UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS | HENKEL AG & CO. KGAA (DE) | 2022-01-27 | — | — | US | disclosed |
| CN-110818903-B | Low-temperature-resistant long-chain hydrocarbon-organic silicon alternating copolymer and preparation method and application thereof | 杭州师范大学 | 2021-09-28 | — | — | CN | disclosed |
| EP-3336129-B1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES | HENKEL AG & CO KGAA (DE) | 2021-03-17 | — | — | EP | disclosed |
| US-20210040269-A1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHER-POLYSILOXANE BLOCK COPOLYMERS | HENKEL AG & CO KGAA (DE) | 2021-02-11 | — | — | US | disclosed |
| CN-112004862-A | Process for preparing hydroxy-functionalized polyether-polysiloxane block copolymers | 汉高股份有限及两合公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110818903-A | Low-temperature-resistant long-chain hydrocarbon-organic silicon alternating copolymer and preparation method and application thereof | 杭州师范大学 | 2020-02-21 | — | — | CN | disclosed |
| US-20190322808-A1 | Process for the Preparation of Hydroxyl-Functionalized Polysiloxanes | LEIBNIZ-INSTITUT FUR KATALYSE E.V. (LIKAT) (DE) | 2019-10-24 | — | — | US | disclosed |
| EP-3336129-A1 | PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES | Henkel AG & Co. KGaA (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1114824-B1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6284907-B1 | REACTING HYDROGEN HALIDE WITH THE CORRESPONDING 1,3-DIHYDRO-1,1,3,3-TETRA(ORGANYL)DISILOXANES; CATALYST SELECTED FROM TRANSITION METALS OF THE 8TH SUBGROUP OF THE PERIODIC TABLE OF THE ELEMENTS, OR COMPOUNDS OR COMPLEXES | WACKER-CHEMIE GMBH (DE) | 2001-09-04 | — | — | US | disclosed |
| EP-1114824-A1 | Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes | Wacker-Chemie GmbH (DE) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11326027-B2 | Process for the preparation of hydroxyl-functionalized polysiloxanes | C9, HACL2, ADH1C | TSHR 1408/4885LMNA 929/4885THRB 1833/4885 |
| US-20190322808-A1 | Process for the Preparation of Hydroxyl-Functionalized Polysiloxanes | C9, HACL2, ADH1C | TSHR 1408/4885LMNA 929/4885THRB 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.