Biphenyl

Biphenyl

SCHEMBL7768930

C=C(C)C(=O)OC#N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 3/20 0.41
DHODH Q02127 2/20 0.40
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 2/20 0.35
CYP1A2 P05177 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
CYP2C19 P33261 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
MAOB P27338 1/20 0.35
PTGS2 P35354 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA4 P48058 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107398 0.82
Methane SCHEMBL27797068 0.80
SCHEMBL30132881 0.79 SMN1; SMN2 (0.43) SMN1; SMN2MAPTKDM4ECYP1A2CYP2C9
Biphenyl SCHEMBL1395450 0.77 ALDH1A1 (0.62) ELANESMN1; SMN2MAPTALDH1A1KDM4E
Biphenyl SCHEMBL9172718 0.76 SMN1; SMN2 (0.54) SMN1; SMN2MAPTDHODHALDH1A1KDM4E
SCHEMBL31190194 0.74 PDCD1 (0.53) SMN1; SMN2MAPTKDM4ECYP1A2PDCD1
SCHEMBL27786451 0.74 TDP1 (0.46) ELANESMN1; SMN2MAPTALDH1A1KDM4E
Biphenyl SCHEMBL473586 0.74 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4ETP53
Biphenyl SCHEMBL28980207 0.74 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4ETP53
Biphenyl SCHEMBL29002594 0.74 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563403-B1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORP (JP) 2001-05-30 EP disclosed
US-5769393-A Liquid crystal elements and method of producing same SEIKO EPSON CORPORATION (JP) 1998-06-23 US disclosed
EP-0563403-A1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORPORATION (JP) 1993-10-06 EP disclosed