Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CDC42 | P60953 | 1/20 | 0.45 |
| ▸ | RAC1 | P63000 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763880 | 0.86 | KMT2A (0.48) | KDM4EMEN1KMT2AESR1CASP3 | |
| SCHEMBL7136988 | 0.83 | KDM4E (0.50) | KDM4EMEN1KMT2ACASP3SENP7 | |
| SCHEMBL7768952 | 0.83 | MAPT (0.50) | KDM4ECYP1A2MEN1KMT2ANPC1 | |
| SCHEMBL9622025 | 0.79 | SMN1; SMN2 (0.59) | KDM4EHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL15086617 | 0.77 | CYP1A2 (0.60) | KDM4EHSD17B1HSD17B2AKR1C3AKR1C2 | |
| SCHEMBL2944091 | 0.75 | KDM4E (0.47) | KDM4EHSD17B1HSD17B2AKR1C3AKR1C2 | |
| SCHEMBL2964316 | 0.74 | NPC1 (0.54) | KDM4ECYP1A2MEN1KMT2ACASP3 | |
| SCHEMBL12641829 | 0.74 | NPC1 (0.54) | KDM4ECYP1A2MEN1KMT2ACASP3 | |
| SCHEMBL8525039 | 0.74 | MTNR1A (0.54) | KDM4EPTGS1CYP1A2MEN1KMT2A | |
| SCHEMBL7516254 | 0.73 | KMT2A (0.42) | KDM4ETSHRMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |