Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767526 | 0.93 | ENPP3 (0.38) | TP53OPRM1OPRD1MAOBRAB9A | |
| SCHEMBL7768559 | 0.88 | PTPN1 (0.35) | LTA4HMEN1KMT2A | |
| SCHEMBL7769000 | 0.83 | HTT (0.36) | MAOBALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL7767591 | 0.83 | MAOB (0.46) | TP53OPRM1OPRD1MAOBBCHE | |
| SCHEMBL13108195 | 0.82 | TAAR1 (0.40) | HRH3ALDH1A1 | |
| SCHEMBL13595464 | 0.82 | TAAR1 (0.40) | HRH3ALDH1A1 | |
| SCHEMBL7768553 | 0.80 | CA1 (0.37) | TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7764003 | 0.80 | APP (0.37) | TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL7768516 | 0.79 | APP (0.35) | LTA4H | |
| SCHEMBL7767015 | 0.78 | ALDH1A1 (0.38) | TP53NPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741128-B1 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | HOFFMANN LA ROCHE (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-5830920-A | PREVENTION GROWTH OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0741128-A2 | Sulphuric acid esters of sugar alcohols for the inhibition of the migration and proliferation of smooth muscle cells of the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |