SCHEMBL7769050

SCHEMBL7769050

Cc1onc(-c2ccc(C(=O)O)cc2)c1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 4/20 0.50
POLB P06746 2/20 0.50
MAPK1 P28482 2/20 0.50
ALOX15 P16050 1/20 0.50
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 2/20 0.49
GPBAR1 Q8TDU6 1/20 0.49
ALDH1A1 P00352 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
USP2 O75604 1/20 0.48
GABRA5 P31644 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862966 0.88 KMT2A (0.59) KMT2AMEN1GAATSHRPOLB
SCHEMBL12310938 0.87 KMT2A (0.58) KMT2AMEN1GAATSHRPOLB
SCHEMBL316093 0.86 KMT2A (0.76) KMT2AMEN1GAATSHRPOLB
SCHEMBL1246411 0.85 KMT2A (0.56) KMT2AMEN1GAATSHRPOLB
SCHEMBL457706 0.85 GPBAR1 (0.59) KMT2AMEN1GAATSHRNPC1
SCHEMBL7771555 0.85 KMT2A (0.60) KMT2AMEN1GAATSHRPOLB
SCHEMBL3548012 0.85 GPBAR1 (0.66) KMT2AMEN1GAATSHRPOLB
Hydrochloric Acid SCHEMBL4846563 0.85 KMT2A (0.73) KMT2AMEN1GAATSHRPOLB
Hydrochloric Acid SCHEMBL3981907 0.84 GPBAR1 (0.57) KMT2AMEN1GAATSHRNPC1
SCHEMBL6069148 0.83 SMN1; SMN2 (0.62) KMT2AMEN1GAATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897540-B1 METHOD FOR DETECTING AND/OR QUANTIFYING A HAPTEN IN A HOMOGENEOUS PHASE AND DEVICE FOR IMPLEMENTATION THEREOF WALLONE REGION (BE) 2001-07-04 EP disclosed
EP-0897540-A1 METHOD FOR DETECTING AND/OR QUANTIFYING A HAPTEN IN A HOMOGENEOUS PHASE AND DEVICE FOR IMPLEMENTATION THEREOF LA REGION WALLONNE (BE) 1999-02-24 EP disclosed
WO-1997041435-A1 METHOD FOR DETECTING AND/OR QUANTIFYING A HAPTEN IN A HOMOGENEOUS PHASE AND DEVICE FOR IMPLEMENTATION THEREOF LA REGION WALLONNE (BE) 1997-11-06 WO disclosed