SCHEMBL316093

SCHEMBL316093

Cc1onc(-c2ccccc2)c1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.76
MEN1 O00255 1/20 0.76
GAA P10253 1/20 0.76
TSHR P16473 4/20 0.62
HTT P42858 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
POLB P06746 2/20 0.62
MAPK1 P28482 2/20 0.61
USP2 O75604 1/20 0.61
ALDH1A1 P00352 2/20 0.59
ALOX15 P16050 1/20 0.59
LMNA P02545 1/20 0.58
GPBAR1 Q8TDU6 1/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4846563 0.98 KMT2A (0.73) KMT2AMEN1GAATSHRHTT
SCHEMBL27722453 0.89 KMT2A (0.76) KMT2AMEN1GAATSHRHTT
SCHEMBL3862966 0.88 KMT2A (0.59) KMT2AMEN1GAATSHRHTT
SCHEMBL1574735 0.88 KMT2A (0.73) KMT2AMEN1GAATSHRHTT
SCHEMBL6069148 0.86 SMN1; SMN2 (0.62) KMT2AMEN1GAATSHRHTT
SCHEMBL7608812 0.86 KMT2A (0.71) KMT2AMEN1GAATSHRHTT
SCHEMBL892042 0.86 KMT2A (0.71) KMT2AMEN1GAATSHRHTT
SCHEMBL7769050 0.86 KMT2A (0.58) KMT2AMEN1GAATSHRHTT
SCHEMBL903110 0.86 KMT2A (1.00) KMT2AMEN1GAATSHRHTT
SCHEMBL10929681 0.86 KMT2A (0.71) KMT2AMEN1GAATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119790158-A Methods and compositions relating to the synthesis of QS-7 molecules 植物生物科学有限公司 2025-04-08 CN claimed
CN-119546753-A Saponin biosynthetic enzymes 植物生物科学有限公司 2025-02-28 CN claimed
CN-117062914-A Methods and compositions 植物生物科学有限公司 2023-11-14 CN claimed
CN-110642801-A Preparation method of parecoxib meta-isomer impurity 深圳市祥根生物科技有限公司 2020-01-03 CN claimed
US-20180273906-A1 MICROVESICLE AND STEM CELL COMPOSITIONS FOR THERAPEUTIC APPLICATIONS IPS HEART 2018-09-27 US claimed
US-20150080408-A1 PYRIDINYL AMIDES AS P2X3 AND P2X2/3 INHIBITORS ROCHE PALO ALTO LLC (US) 2015-03-19 US claimed
US-8809326-B2 Isoquinolinone Rho kinase inhibitors AERIE PHARMACEUTICALS, INC. (US) 2014-08-19 US claimed
EP-2445868-B1 BIPHENYL AMIDES USEFUL AS P2X3 AND/OR P2X2/3 RECEPTORS MODULATORS HOFFMANN LA ROCHE (CH) 2013-12-18 EP claimed
US-20130165443-A1 BIPHENYL AND PHENYL-PYRIDINE AMIDES AS P2X3 AND P2X2/3 ANTAGONISTS BROKA CHRIS ALLEN (US) 2013-06-27 US claimed
EP-1745009-B1 HETEROARYL SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES GRUENENTHAL GMBH (DE) 2012-11-14 EP claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1998034111-A1 TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1998002741-A9 QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES 1998-05-22 WO claimed
WO-1998002741-A1 QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-01-22 WO claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180273906-A1 MICROVESICLE AND STEM CELL COMPOSITIONS FOR THERAPEUTIC APPLICATIONS EXOSC9, EXOSC5, EXOSC4 KMT2A 2981/4885MEN1 2441/4885GAA 562/4885
US-20150080408-A1 PYRIDINYL AMIDES AS P2X3 AND P2X2/3 INHIBITORS P2RX3, P2RX2, P2RX1 KMT2A 3676/4885MEN1 2785/4885GAA 3642/4885
US-20130165443-A1 BIPHENYL AND PHENYL-PYRIDINE AMIDES AS P2X3 AND P2X2/3 ANTAGONISTS P2RX3, P2RX2, P2RX7 KMT2A 2959/4885MEN1 3518/4885GAA 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.