Acrylic Acid

Acrylic Acid

SCHEMBL7769059

C=CC(=O)O.NS(=O)(=O)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
TSHR P16473 5/20 0.40
ALDH1A1 P00352 2/20 0.40
FGFR4 P22455 1/20 0.40
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
NT5E P21589 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
EGLN3 Q9H6Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL4558624 0.88 LMNA (0.67) LMNATSHRALDH1A1FGFR4ALOX15
Acrylic Acid SCHEMBL29175486 0.82 LMNA (0.59) LMNATSHRALDH1A1FGFR4ALOX15
Trifluoromethanesulfonamide SCHEMBL25383981 0.81 CA1 (0.55) LMNATSHRALDH1A1FGFR4ALOX15
Acrylic Acid SCHEMBL3399482 0.78 LMNA (0.71) LMNATSHRALDH1A1FGFR4ALOX15
Acrylic Acid SCHEMBL8522897 0.77
Acrylic Acid SCHEMBL28146539 0.77
Acrylic Acid SCHEMBL2481347 0.77
Acrylic Acid SCHEMBL867817 0.77
Acrylic Acid SCHEMBL4371336 0.77
Acrylic Acid SCHEMBL8580358 0.77 LMNA (1.00) LMNATSHRALDH1A1FGFR4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109846-A1 CONTACT LENS MATERIAL UNISEARCH LIMITED (AU) 2001-06-27 EP disclosed
WO-2000004065-A1 CONTACT LENS MATERIAL UNISEARCH LIMITED (AU) 2000-01-27 WO disclosed