Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA4 | P22748 | 6/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042111 | 0.87 | CA12 (0.48) | CA12CA1CA2CA4RORC | |
| SCHEMBL8055910 | 0.83 | MEN1 (0.47) | CA12CA1CA2TSHRUSP2 | |
| SCHEMBL8530542 | 0.81 | CNR2 (0.52) | CA12CA1CA2CA4RORC | |
| SCHEMBL11208914 | 0.79 | ALDH1A1 (0.41) | CA12CA1CA2CA4USP2 | |
| SCHEMBL11212081 | 0.79 | CYP2C19 (0.44) | CA12CA1CA2RORCUSP2 | |
| SCHEMBL11660111 | 0.79 | CA12 (0.43) | CA12CA1CA2CA4RORC | |
| SCHEMBL11209028 | 0.77 | KCNH2 (0.41) | CA12CA1CA2CA4RORC | |
| SCHEMBL2323987 | 0.76 | USP2 (0.53) | TSHRUSP2HSD17B10MEN1KMT2A | |
| SCHEMBL11213571 | 0.76 | KCNH2 (0.47) | CYP1A2CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL10795140 | 0.75 | HSD17B10 (0.48) | CA12CA1CA2USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |