Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Telmesteine SCHEMBL1425417 | 0.85 | ACE (0.53) | GAAPREPACETSHR | |
| SCHEMBL7769271 | 0.83 | PREP (0.40) | GAAPREPACETSHRDPP4 | |
| SCHEMBL7771045 | 0.83 | TSHR (0.41) | PREPCNR2ACETSHRDPP4 | |
| SCHEMBL1021093 | 0.79 | ATM (0.44) | PREPCNR2ACECHRM1 | |
| SCHEMBL3509553 | 0.79 | ATM (0.44) | PREPCNR2ACECHRM1 | |
| SCHEMBL3509552 | 0.79 | ATM (0.44) | PREPCNR2ACECHRM1 | |
| SCHEMBL11197416 | 0.77 | GAA (0.49) | GAACHRM1ALOX15TSHRNOS3 | |
| SCHEMBL6002706 | 0.74 | ACE (0.40) | PREPCNR2ACEDPP4 | |
| SCHEMBL1022056 | 0.74 | ACE (0.40) | PREPCNR2ACEDPP4 | |
| SCHEMBL21101788 | 0.74 | ACE (0.37) | PREPCNR2ACEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077110-C | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| CN-1153177-A | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 1997-07-02 | — | — | CN | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |