Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Telmesteine SCHEMBL1425417 | 0.85 | ACE (0.53) | PREPACETSHRRECQLGAA | |
| SCHEMBL7769272 | 0.83 | GAA (0.42) | PREPACETSHRGAADPP4 | |
| SCHEMBL7771040 | 0.83 | TSHR (0.41) | PREPACETSHRDPP4ATM | |
| SCHEMBL9879848 | 0.79 | ATM (0.44) | PREPACERECQLATM | |
| SCHEMBL25122274 | 0.73 | PRCP (0.45) | TSHR | |
| SCHEMBL7268458 | 0.72 | PREP (0.37) | PREPACETSHRGAADPP4 | |
| SCHEMBL6706811 | 0.72 | ACE (0.47) | PREPACETSHRATM | |
| SCHEMBL7771058 | 0.71 | RAB9A (0.53) | PREPTSHRGAAATM | |
| SCHEMBL4649343 | 0.70 | HSD17B10 (0.42) | PREPACETSHRGAADPP4 | |
| SCHEMBL7051453 | 0.70 | ALDH1A1 (0.41) | ACEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |