Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767878 | 0.91 | MAPT (0.34) | CA12CA2CA9KMT2AMEN1 | |
| SCHEMBL7764264 | 0.85 | MAPT (0.33) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL7764275 | 0.84 | GSK3B (0.38) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL7764292 | 0.84 | CNR2 (0.32) | KMT2AMAPTNPC1RAB9APSMD14 | |
| SCHEMBL13029845 | 0.72 | ALDH1A1 (0.44) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL13070309 | 0.72 | TDP1 (0.39) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL597248 | 0.72 | ALDH1A1 (0.39) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL12492278 | 0.72 | ALDH1A1 (0.39) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11150290 | 0.71 | CA12 (0.53) | CA12CA2CA9GLO1KMT2A | |
| SCHEMBL7758370 | 0.71 | CA12 (0.53) | CA12CA2CA9GLO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | claimed |
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |