Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767878 | 0.90 | MAPT (0.34) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7764292 | 0.90 | CNR2 (0.32) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7764275 | 0.90 | GSK3B (0.38) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7769282 | 0.85 | CA12 (0.41) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7769138 | 0.83 | MAPT (0.40) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7769136 | 0.83 | MAPT (0.40) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL8727698 | 0.81 | ALDH1A1 (0.33) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7768058 | 0.76 | NPC1 (0.44) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7768059 | 0.76 | NPC1 (0.44) | MAPTNPC1RAB9AKMT2APSMD14 | |
| SCHEMBL7768204 | 0.73 | CRHR1 (0.33) | MAPTKMT2ASMN1; SMN2MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | claimed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |