⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368868 | 0.85 | LMNA (0.41) | — | |
| SCHEMBL15101128 | 0.85 | — | — | |
| SCHEMBL45851 | 0.76 | — | — | |
| SCHEMBL8958822 | 0.73 | — | — | |
| SCHEMBL18044434 | 0.72 | — | — | |
| Iodide SCHEMBL11260489 | 0.71 | — | — | |
| SCHEMBL10798283 | 0.71 | — | — | |
| SCHEMBL9491675 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL12657738 | 0.69 | — | — | |
| SCHEMBL11366438 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113766952-B | Method for producing radiopharmaceutical and radiopharmaceutical | 国立研究开发法人量子科学技术研究开发机构 | 2023-09-08 | — | — | CN | disclosed |
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20220175973-A1 | METHOD FOR PRODUCING RADIOPHARMACEUTICAL AND RADIOPHARMACEUTICAL | National Institutes for Quantum Science and Technology (JP) | 2022-06-09 | — | — | US | disclosed |
| CN-113766952-A | Method for producing radiopharmaceutical and radiopharmaceutical | 国立研究开发法人量子科学技术研究开发机构 | 2021-12-07 | — | — | CN | disclosed |
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |
| US-20200360544-A1 | RADIOACTIVE ANTITUMOR AGENT | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2020-11-19 | — | — | US | disclosed |
| WO-2020202831-A1 | METHOD FOR PRODUCING RADIOPHARMACEUTICAL AND RADIOPHARMACEUTICAL | 国立研究開発法人量子科学技術研究開発機構 | 2020-10-08 | — | — | WO | disclosed |
| CN-111356483-A | Radioactive antitumor agent | 国立研究开发法人量子科学技术研究开发机构 | 2020-06-30 | — | — | CN | disclosed |
| US-20140186260-A1 | RADIOPHARMACEUTICAL AND PHARMACEUTICAL KIT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2014-07-03 | — | — | US | disclosed |
| EP-2749295-A1 | Radiopharmaceutical and pharmaceutical kit | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2014-07-02 | — | — | EP | disclosed |
| US-20130178437-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-11 | — | — | US | disclosed |
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2012-06-14 | — | — | US | disclosed |
| EP-0726077-B1 | Radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative | NIHON MEDIPHYSICS CO LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5843400-A | Diagnostic agent for hypoxia or mitochondrial dysfunction comprising radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0726077-A2 | Radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-4801708-A | FOR AGRICULTURAL USE | CIBA-GEIGY CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0150677-B1 | HERBICIDAL AND INSECTICIDAL TRIAZINONES | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| EP-0150677-A1 | Herbicidal and insecticidal triazinones | CIBA-GEIGY AG (CH) | 1985-08-07 | — | — | EP | disclosed |
| US-4348518-A | Cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |