Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1766712 | 0.98 | — | — | |
| SCHEMBL7765953 | 0.90 | — | — | |
| SCHEMBL29158988 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL11806357 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL995683 | 0.79 | — | — | |
| SCHEMBL27602894 | 0.78 | TSHR (0.39) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL28343443 | 0.78 | TSHR (0.39) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL5463696 | 0.77 | ALDH1A1 (0.37) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL10845203 | 0.76 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4NAAAEPHX1 | |
| SCHEMBL4620117 | 0.76 | NAAA (0.61) | TSHRALDH1A1NAAAEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |