Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828826 | 0.85 | KMT2A (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7770074 | 0.82 | HDAC3 (0.39) | TRPA1ALDH1A1 | |
| SCHEMBL7765959 | 0.79 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL7765728 | 0.79 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7769664 | 0.79 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL7770041 | 0.79 | CES1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7771070 | 0.75 | — | — | |
| SCHEMBL5147124 | 0.75 | — | — | |
| SCHEMBL7770619 | 0.73 | KDM4E (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7765838 | 0.73 | FAAH (0.41) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |