⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765554 | 0.75 | — | — | |
| SCHEMBL44271 | 0.65 | — | — | |
| SCHEMBL11034124 | 0.62 | — | — | |
| SCHEMBL1059697 | 0.62 | — | — | |
| SCHEMBL8625620 | 0.62 | — | — | |
| SCHEMBL8089204 | 0.61 | — | — | |
| SCHEMBL1261826 | 0.60 | — | — | |
| SCHEMBL7646970 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL2869790 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL3961077 | 0.57 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617047-B1 | Dye-labelled phosphoramadites | PE CORP NY (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-0323152-B1 | Method of synthesizing oligonucleotides | APPLIED BIOSYSTEMS (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0617047-A1 | Dye-labelled phosphoramadites | THE PERKIN-ELMER CORPORATION (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5231191-A | Rhodamine phosphoramidite compounds | APPLIED BIOSYSTEMS, INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-4965349-A | HYDROLYSIS OF LINKING GROUP WITH MIXTURE OF ALCOHOL, WATER, AND HINDERED AMINE | APPLIED BIOSYSTEMS, INC. (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0323152-A2 | Method of synthesizing oligonucleotides | APPLIED BIOSYSTEMS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |