Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869790 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E | |
| SCHEMBL3961077 | 0.88 | ALDH1A1 (0.32) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E | |
| SCHEMBL28329574 | 0.85 | CYP2C9 (0.32) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E | |
| Hydrogen Peroxide SCHEMBL139127 | 0.82 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E | |
| Hydrogen Peroxide SCHEMBL139129 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL341831 | 0.82 | — | — | |
| SCHEMBL124190 | 0.82 | — | — | |
| SCHEMBL1736341 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E | |
| SCHEMBL30 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL946877 | 0.78 | ALDH1A1 (0.35) | ALDH1A1CYP2C9HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568696-A | Novel synthesis of phosphorodithioate oligonucleotides | 豪夫迈·罗氏有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-6475985-B1 | Nucleosides with antiviral and anticancer activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-11-05 | — | — | US | disclosed |
| WO-1999049873-A1 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-10-07 | — | — | WO | disclosed |