⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103222 | 1.00 | — | — | |
| SCHEMBL10098537 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL23833329 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL23833331 | 0.97 | — | — | |
| SCHEMBL7770091 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8711333 | 0.84 | GABRP (0.52) | — | |
| SCHEMBL7570352 | 0.84 | GABRP (0.52) | — | |
| Hydrochloric Acid SCHEMBL27458238 | 0.84 | GABRP (0.52) | — | |
| SCHEMBL23772724 | 0.82 | GABRP (0.50) | — | |
| SCHEMBL21345023 | 0.80 | ALOX15 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282867-A1 | INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023119233-A1 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | MOLECURE S.A. (PL) | 2023-06-29 | — | — | WO | disclosed |
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| WO-2019170051-A1 | DACOS TYPE NNRTIS AMINO ACID ESTER DERIVATIVE, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 云南大学 | 2019-09-12 | — | — | WO | disclosed |
| WO-2019147862-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | FLX BIO, INC. (US) | 2019-08-01 | — | — | WO | disclosed |
| CN-109912603-A | A kind of practical approach using N- methoxyamide as nitrogen source synthesizing new bioactive molecule | 苏州大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-108349969-A | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阵列生物制药公司 | 2018-07-31 | — | — | CN | disclosed |
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |
| WO-2014005182-A1 | PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS | MONASH UNIVERSITY (AU) | 2014-01-09 | — | — | WO | disclosed |
| US-8222255-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-07-17 | — | — | US | disclosed |
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |
| CN-1117960-A | Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | CN | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |