Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908640 | 0.82 | HSD17B10 (0.41) | KDM4EPIK3CDNAAAMAPK1FAAH | |
| SCHEMBL15125171 | 0.80 | PIK3CD (0.42) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL4787017 | 0.80 | TSHR (0.48) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL11983582 | 0.80 | PIK3CD (0.42) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL13096630 | 0.77 | NAAA (0.42) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL2825590 | 0.76 | ALDH1A1 (0.41) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL13086572 | 0.76 | PIK3CD (0.40) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL8519079 | 0.76 | NPC1 (0.44) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL15113635 | 0.76 | PIK3CD (0.46) | KDM4EPIK3CDNAAANPC1RAB9A | |
| SCHEMBL631171 | 0.74 | PIK3CD (0.41) | KDM4EPIK3CDNAAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |