Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770881 | 0.98 | ALDH1A1 (0.42) | ACHEMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7770971 | 0.98 | ALDH1A1 (0.42) | ACHEMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7771590 | 0.94 | ACHE (0.42) | ACHEMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL7769360 | 0.88 | ACHE (0.35) | ACHEMAOAMAOBHTT | |
| SCHEMBL19513089 | 0.85 | PRMT1 (0.53) | ACHEKMT2AEPHX2HTTPRMT1 | |
| SCHEMBL7769453 | 0.83 | ACHE (0.40) | ACHEALDH1A1SMN1; SMN2KMT2AEPHX1 | |
| SCHEMBL7770969 | 0.81 | ALDH1A1 (0.41) | ACHEALDH1A1SMN1; SMN2KMT2AEPHX1 | |
| SCHEMBL7770879 | 0.81 | ALDH1A1 (0.41) | ACHEALDH1A1SMN1; SMN2KMT2AEPHX1 | |
| SCHEMBL7771614 | 0.81 | ACHE (0.50) | ACHEMAOAMAOBEPHX1EPHX2 | |
| SCHEMBL15550570 | 0.78 | HTT (0.56) | ACHEKMT2AEPHX2HTTPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |