⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869460 | 0.91 | — | — | |
| SCHEMBL7771357 | 0.76 | — | — | |
| SCHEMBL600282 | 0.71 | BRD4 (0.52) | — | |
| SCHEMBL7769487 | 0.71 | — | — | |
| SCHEMBL2691052 | 0.69 | — | — | |
| SCHEMBL11812299 | 0.67 | — | — | |
| SCHEMBL5339702 | 0.67 | BRD4 (0.42) | — | |
| SCHEMBL6565421 | 0.67 | — | — | |
| SCHEMBL316095 | 0.67 | — | — | |
| SCHEMBL795214 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5204337-A | Estrogen nucleus derivatives for use in inhibition of sex steroid activity | ENDORECHERCHE INC. (CA) | 1993-04-20 | — | — | US | disclosed |
| EP-0257602-A1 | (5R,6S,8R)-6-(1-hydroxyethyl)-2-(3R-pyrolidin-2-one-3-yl-)thiopenem-3-carboxylic acid | SCHERING CORPORATION (US) | 1988-03-02 | — | — | EP | disclosed |