Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.40 |
| ▸ | RXRB | P28702 | 5/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773833 | 0.93 | RXRA (0.39) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL7769492 | 0.90 | RXRA (0.44) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL6733036 | 0.85 | RARB (0.48) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL7769521 | 0.84 | PPARG (0.40) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL7771635 | 0.82 | RXRA (0.42) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL6737755 | 0.81 | RXRA (0.57) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL6733888 | 0.80 | CYP3A4 (0.45) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL7769613 | 0.79 | RXRA (0.40) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL6737119 | 0.76 | RXRA (0.55) | RXRARXRBCYP26A1CYP26B1RXRG | |
| SCHEMBL7769865 | 0.74 | RXRA (0.36) | RXRARXRBCYP26A1CYP26B1RXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | claimed |