Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769521 | 0.92 | PPARG (0.40) | RXRACYP26A1CYP26B1RXRBPPARG | |
| SCHEMBL7771786 | 0.88 | RXRA (0.44) | RXRACYP26A1CYP26B1RXRBCYP3A4 | |
| SCHEMBL7771646 | 0.85 | RXRA (0.41) | RXRARXRBPPARGCYP3A4RXRG | |
| SCHEMBL7773833 | 0.84 | RXRA (0.39) | RXRACYP26A1CYP26B1RXRBPPARG | |
| SCHEMBL7770182 | 0.83 | PPARG (0.37) | RXRACYP26A1CYP26B1RXRBPPARG | |
| SCHEMBL6729936 | 0.83 | CYP3A4 (0.49) | RXRACYP26A1CYP26B1RXRBCYP3A4 | |
| SCHEMBL7769865 | 0.81 | RXRA (0.36) | RXRACYP26A1CYP26B1RXRBPPARG | |
| SCHEMBL7771769 | 0.81 | RXRA (0.44) | RXRACYP26A1CYP26B1RXRBPPARG | |
| SCHEMBL7771740 | 0.80 | RARA (0.44) | PPARGRARBRARGRARA | |
| SCHEMBL7769610 | 0.79 | RXRA (0.40) | RXRACYP26A1CYP26B1RXRBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | claimed |