⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556151 | 0.80 | LMNA (0.37) | — | |
| SCHEMBL1269148 | 0.75 | — | — | |
| SCHEMBL432595 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6600516 | 0.73 | LMNA (0.33) | — | |
| SCHEMBL575197 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL10621774 | 0.71 | — | — | |
| SCHEMBL1041196 | 0.71 | — | — | |
| SCHEMBL9761916 | 0.71 | — | — | |
| SCHEMBL400162 | 0.69 | — | — | |
| SCHEMBL4551584 | 0.69 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-A | For treating the PGI2 receptor modulators of prostacyclin (PGI2) receptor associate disorder | 艾尼纳制药公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-104262267-B9 | PGI2 receptor modulators for the treatment of prostacyclin (PGI2) receptor-related disorders | 艾尼纳制药公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-104262267-B | For treating the PGI2 receptor modulators of prostacyclin (PGI2) receptor associate disorder | 艾尼纳制药公司 | 2019-02-26 | — | — | CN | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |