SCHEMBL7769771

SCHEMBL7769771

CC(C)(C)C(=O)CC(O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.39
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23326065 0.80 CETP (0.42) CETPPKM
SCHEMBL12081424 0.80 TSHR (0.43) CYP2C19
SCHEMBL24172967 0.78 KMT2A (0.30)
SCHEMBL17886857 0.76
SCHEMBL12965457 0.75 ALDH1A1 (0.43) CETPPKMCYP2C19
SCHEMBL26798776 0.74
SCHEMBL10335818 0.74 CETP (0.46) CETPPKMCYP2C19
SCHEMBL9748359 0.74 KMT2A (0.33) CYP2C19
SCHEMBL10335654 0.74 CETP (0.46) CETPPKMCYP2C19
SCHEMBL16018053 0.74 SLC22A6 (0.43) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821679-B1 ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE CHIROTECH TECHNOLOGY LTD (GB) 2001-07-11 EP disclosed
EP-0821679-A1 ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE Chiroscience Limited (GB) 1998-02-04 EP disclosed
WO-1996033183-A1 ASYMMETRIC EPOXIDES, THEIR SYNTHESIS AND USE CHIROSCIENCE LIMITED (GB) 1996-10-24 WO disclosed