Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018053 | 0.82 | SLC22A6 (0.43) | KMT2ASLC22A6HSD11B1CYP2C19 | |
| SCHEMBL14035478 | 0.80 | MAPK1 (0.35) | KMT2AALDH1A1CYP2C19 | |
| SCHEMBL13543295 | 0.80 | MAPK1 (0.35) | KMT2AALDH1A1CYP2C19 | |
| SCHEMBL12081424 | 0.78 | TSHR (0.43) | KMT2ACYP2C19 | |
| SCHEMBL269050 | 0.77 | ALDH1A1 (0.48) | KMT2AALDH1A1CYP2C19 | |
| SCHEMBL23847056 | 0.76 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL14321928 | 0.76 | TSHR (0.36) | KMT2ASLC22A6 | |
| SCHEMBL14321595 | 0.76 | CYP2D6 (0.34) | KMT2AALDH1A1CYP2C19 | |
| SCHEMBL13995536 | 0.76 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL7769771 | 0.74 | CETP (0.39) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482080-A1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS. | GENENTECH INC (US) | 1992-04-29 | — | — | EP | disclosed |
| WO-1991001331-A1 | SMALL CYCLIC PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1991-02-07 | — | — | WO | disclosed |