SCHEMBL7769810

SCHEMBL7769810

O=C(Oc1cc(O)ccc1C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.75
ESR2 Q92731 3/20 0.75
ALDH1A1 P00352 3/20 0.53
LMNA P02545 2/20 0.53
NSD2 O96028 1/20 0.51
MAPT P10636 6/20 0.50
SLC6A3 Q01959 2/20 0.50
HSD17B10 Q99714 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CHRM1 P11229 1/20 0.50
TBXA2R P21731 1/20 0.50
SLC6A2 P23975 1/20 0.50
PDE4A P27815 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9494739 0.88 KMT2A (0.68) ESR1ESR2ALDH1A1MAPTSLC6A3
SCHEMBL5179548 0.86 ESR1 (1.00) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL7615928 0.85 ESR1 (0.75) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL7769807 0.83 ALDH1A1 (0.62) ESR1ESR2ALDH1A1LMNANSD2
SCHEMBL4386437 0.82 ALDH1A1 (0.73) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL9495452 0.82 ESR1 (0.66) ESR1ESR2ALDH1A1LMNAMAPT
Hydroquinone SCHEMBL9490244 0.82 PARP10 (0.61) ESR1ESR2ALDH1A1LMNANSD2
SCHEMBL6564075 0.81 ESR1 (0.69) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL6564045 0.81 ESR1 (0.69) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL6565963 0.81 ESR1 (0.69) ESR1ESR2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-0748698-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 2001-08-22 EP disclosed
US-6184300-B1 USEFUL AS HEAT-INSULATING MATERIAL, ORGANIC PIGMENT, OR OPACIFYING AGENT, AND AS HEAT-INSULATING INTERLAYER TO BE FORMED IN THERMAL RECORDING MATERIAL NIPPON ZEON CO., LTD. (JP) 2001-02-06 US disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5747414-A SUBSTRATE WITH COLOR LAYER, ALUMINUM HYDROXIDE AND A RESIN OF UREA-FORMALDEHYDE AND DEVELOPERS NIPPON PAPER INDUSTRIES, LTD. (JP) 1998-05-05 US disclosed
US-5665675-A THERMAL RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-09-09 US disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0693386-B1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials JUJO PAPER CO LTD (JP) 1997-02-05 EP disclosed
EP-0559386-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-01-15 EP disclosed
EP-0748698-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-12-18 EP disclosed
US-5322831-A Color developers, chromogenic dye, stabilizer and sensitizer JUJO PAPER CO., LTD. (JP) 1994-06-21 US disclosed
EP-0559386-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-08 EP disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
US-4971942-A Colorless basic chromogenic cye, divinyl compound, fluorane-type leuco dye JUJO PAPER CO., LTD. (JP) 1990-11-20 US disclosed
EP-0391434-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1990-10-10 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
US-4853362-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1989-08-01 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed