Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427602 | 0.85 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4427604 | 0.85 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4665329 | 0.85 | TTR (0.55) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4665327 | 0.85 | TTR (0.55) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL27414274 | 0.84 | TTR (0.53) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL10267949 | 0.83 | POLB (0.53) | TTRDPP4MEN1KMT2AALDH1A1 | |
| SCHEMBL7772753 | 0.82 | CA12 (0.67) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL1269502 | 0.81 | TTR (0.63) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL3752885 | 0.81 | CA12 (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL1269501 | 0.81 | TTR (0.63) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912509-B1 | DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN SPA (IT) | 2001-07-11 | — | — | EP | disclosed |
| US-6177408-B1 | COMPOUNDS SUCH AS 3-(1-METHYL-4(1-METHYL-4(1-METHYL-4(4-N,N-BIS(2 -CHLOROETHYL)AMINOCINNAMOYLAMIDO)PYRROLE-2-CARBOXAMIDO)PYRROLE-2 -CARBOXAMIDO)PYRROLE-2-CARBOXAMIDO)PROPIONAMIDINE | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |
| EP-0912509-A1 | DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043258-A1 | DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-11-20 | — | — | WO | disclosed |