Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665327 | 1.00 | TTR (0.55) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL10895023 | 0.86 | SIRT2 (0.57) | TTRMAPTLMNATP53SMN1; SMN2 | |
| SCHEMBL7769917 | 0.85 | TTR (0.56) | TTRDPP4MAPTNPC1RAB9A | |
| SCHEMBL4427602 | 0.84 | TTR (0.69) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL4427604 | 0.84 | TTR (0.69) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL10262541 | 0.84 | HDAC3 (0.54) | TTRDPP4MAPTLMNASMN1; SMN2 | |
| SCHEMBL2630687 | 0.84 | PKM (0.56) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL6984318 | 0.83 | CA12 (0.65) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL6984316 | 0.83 | CA12 (0.65) | TTRDPP4MAPTLMNATP53 | |
| SCHEMBL27414274 | 0.83 | TTR (0.53) | TTRDPP4MAPTTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275274-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2008-11-06 | — | — | US | disclosed |
| US-20050245756-A1 | Process for the preparation of enantiomerically enriched compounds | DSM IP ASSETS B.V. (NL) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245756-A1 | Process for the preparation of enantiomerically enriched compounds | AR, NPR3, LMNA | TTR 854/4885DPP4 4376/4885MAPT 3237/4885 |
| US-20080275274-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED COMPOUNDS | AR, TAC3, AOC3 | TTR 2538/4885DPP4 3140/4885MAPT 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.