Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.33 |
| ▸ | PDE2A | O00408 | 5/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769939 | 1.00 | EPHX2 (0.33) | EPHX2PDE2AKDM1ACYP2C9ALDH1A1 | |
| SCHEMBL7769945 | 1.00 | EPHX2 (0.33) | EPHX2PDE2AKDM1ACYP2C9ALDH1A1 | |
| SCHEMBL7765429 | 0.92 | KDM1A (0.31) | KDM1ACYP2C9 | |
| SCHEMBL7765427 | 0.92 | KDM1A (0.31) | KDM1ACYP2C9 | |
| SCHEMBL8417305 | 0.91 | PDE2A (0.34) | EPHX2PDE2AKDM1ACYP2C9ALDH1A1 | |
| SCHEMBL8417308 | 0.91 | PDE2A (0.34) | EPHX2PDE2AKDM1ACYP2C9ALDH1A1 | |
| SCHEMBL8022432 | 0.88 | CTSK (0.33) | EPHX2PDE2ACYP2C9 | |
| SCHEMBL8022434 | 0.88 | CTSK (0.33) | EPHX2PDE2ACYP2C9 | |
| SCHEMBL9008550 | 0.88 | CTSK (0.33) | EPHX2PDE2ACYP2C9 | |
| SCHEMBL8022431 | 0.88 | CTSK (0.33) | EPHX2PDE2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |