⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010135 | 0.71 | — | — | |
| SCHEMBL2006039 | 0.70 | — | — | |
| SCHEMBL7993528 | 0.69 | — | — | |
| SCHEMBL507597 | 0.69 | — | — | |
| SCHEMBL4660784 | 0.67 | — | — | |
| SCHEMBL2377189 | 0.65 | CA1 (0.37) | — | |
| SCHEMBL10934685 | 0.65 | — | — | |
| SCHEMBL5556928 | 0.65 | ALDH1A1 (0.44) | — | |
| SCHEMBL11155721 | 0.64 | — | — | |
| SCHEMBL3142222 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334590-B1 | 3-(Substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor | LILLY CO ELI (US) | 2001-07-04 | — | — | EP | disclosed |
| EP-0565351-B1 | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters | LILLY CO ELI (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0494118-B1 | Process for 3-exomethylenecepham sulfoxide esters | LILLY CO ELI (US) | 1997-04-09 | — | — | EP | disclosed |
| US-5512454-A | Enzymatic acylation of 3-hydroxymethyl cephalosporins | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0677523-A1 | 3-(substituted)-1-carba(dethia)-3-cephems and cephalosporins and a process for production therefor | ELI LILLY AND COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0667396-A1 | Enzymatic acylation of 3-hydroxymethyl cephalosporins | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0334592-B1 | A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins | LILLY CO ELI (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5350845-A | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters | ELI LILLY AND COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0611770-A2 | A process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0327239-B1 | 1-carbacephalosporin antibiotics | LILLY CO ELI (US) | 1994-06-22 | — | — | EP | disclosed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4203897-A | Penam derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4113940-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3988325-A | 7-Carboxy or 2,2,2-trichloroethoxy carbonyl- cephalosporins | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3962214-A | Process for preparing amino substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954731-A | Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids | ELI LILLY AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |