Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 13/20 | 0.44 |
| ▸ | HNF4A | P41235 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 5/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 4/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770208 | 1.00 | CYP26A1 (0.47) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL6736673 | 0.91 | CYP3A4 (0.48) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL6736672 | 0.91 | CYP3A4 (0.48) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL7769471 | 0.83 | CYP26A1 (0.50) | CYP26A1CYP26B1CYP3A4RXRARXRB | |
| SCHEMBL7769473 | 0.83 | CYP26A1 (0.50) | CYP26A1CYP26B1CYP3A4RXRARXRB | |
| SCHEMBL7794236 | 0.81 | CYP26A1 (0.70) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL7803974 | 0.79 | CYP26A1 (0.55) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL8773679 | 0.76 | RARB (0.53) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL8773722 | 0.76 | RARB (0.53) | CYP26A1CYP26B1CYP3A4RXRAHNF4A | |
| SCHEMBL8773686 | 0.76 | RARB (0.53) | CYP26A1CYP26B1CYP3A4RXRAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | disclosed |
| EP-0823903-A1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-02-18 | — | — | EP | disclosed |
| WO-1997029100-A1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-08-14 | — | — | WO | disclosed |