Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.70 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.70 |
| ▸ | RXRA | P19793 | 11/20 | 0.52 |
| ▸ | RXRB | P28702 | 9/20 | 0.52 |
| ▸ | RARB | P10826 | 7/20 | 0.52 |
| ▸ | RARG | P13631 | 6/20 | 0.52 |
| ▸ | RXRG | P48443 | 6/20 | 0.52 |
| ▸ | RARA | P10276 | 5/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092497 | 0.91 | CYP26A1 (0.70) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL6732613 | 0.89 | CYP3A4 (0.71) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7803974 | 0.89 | CYP26A1 (0.55) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7810742 | 0.84 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7769473 | 0.84 | CYP26A1 (0.50) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7769471 | 0.84 | CYP26A1 (0.50) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL5078193 | 0.83 | CYP26A1 (1.00) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7770208 | 0.81 | CYP26A1 (0.47) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL7770210 | 0.81 | CYP26A1 (0.47) | CYP26A1CYP3A4CYP26B1RXRARXRB | |
| SCHEMBL6733878 | 0.80 | CYP3A4 (0.71) | CYP26A1CYP3A4CYP26B1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882033-B1 | BENZOFURAN-ACRYLIC ACID DERIVATIVES AND THEIR USE AS MODULATORS OF RXRS OR RARS RECEPTORS | CT INTERNAT DE RECH S (FR) | 2001-08-16 | — | — | EP | disclosed |