Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26950788 | 0.81 | TDP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL31690837 | 0.81 | TDP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL24414474 | 0.81 | TDP1 (0.39) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL305578 | 0.81 | SMN1; SMN2 (0.48) | OR51E2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL5179489 | 0.79 | OR51E2 (0.48) | OR51E2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL26073653 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL10879307 | 0.78 | OR51E2 (0.46) | OR51E2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL18219230 | 0.78 | SMN1; SMN2 (0.44) | OR51E2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL16928435 | 0.78 | SMN1; SMN2 (0.44) | OR51E2SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL18219117 | 0.74 | MMP1 (0.44) | OR51E2SMN1; SMN2MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831774-B1 | ORAL DOSAGE AND METHOD FOR TREATING PAINFUL CONDITIONS OF THE ORAL CAVITY | ALZA CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| US-5897878-A | ORALLY ADMINISTERING DELIVERY SYSTEM IN WHICH FLUID IMBIBITION CAUSES HYDROPHILIC POLYMER TO AGGREGATE IN SITU IN PRESENCE OF POLYHYDROXY COMPOUND AND CAUSES PUSH LAYER TO ABSORB FLUID AND DELIVER AGGREGATES CONTAINING STEROID | ALZA CORPORATION (US) | 1999-04-27 | — | — | US | disclosed |
| US-5830501-A | DRUG DELIVERY TO MUCOSAL TISSUE, SEMIPERMEABLE WALL, PRECIPITATION | ALZA CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0831774-A1 | ORAL DOSAGE AND METHOD FOR TREATING PAINFUL CONDITIONS OF THE ORAL CAVITY | ALZA CORPORATION (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5713852-A | Oral dosage and method for treating painful conditions of the oral cavity | ALZA CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| WO-1996040050-A1 | ORAL DOSAGE AND METHOD FOR TREATING PAINFUL CONDITIONS OF THE ORAL CAVITY | ALZA CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5266332-A | Oral administering of drugs with semipermeable walls and multicompartment polymer with electrolyte | ALZA CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| US-5254349-A | Flocculating drug and hydrophilic polymer in dosage form | ALZA CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| US-5200195-A | Reducing stickiness of a dosage for to biological tissue in fluid environment of use | ALZA CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |