Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770286 | 1.00 | NAAA (0.36) | NAAACTSKFFAR4HCRTR1HCRTR2 | |
| SCHEMBL8019072 | 0.94 | NAAA (0.34) | NAAACTSKFFAR4HCRTR1HCRTR2 | |
| SCHEMBL8019070 | 0.94 | NAAA (0.34) | NAAACTSKFFAR4HCRTR1HCRTR2 | |
| SCHEMBL8034197 | 0.87 | NAAA (0.40) | NAAACTSKFFAR4HCRTR1HCRTR2 | |
| SCHEMBL8021369 | 0.85 | CYP17A1 (0.37) | CYP17A1RARBRARARARG | |
| SCHEMBL8021366 | 0.85 | CYP17A1 (0.37) | CYP17A1RARBRARARARG | |
| SCHEMBL8748046 | 0.84 | RARB (0.39) | NAAACTSKFFAR4HCRTR1HCRTR2 | |
| SCHEMBL9013302 | 0.84 | HCRTR1 (0.33) | NAAACTSKHCRTR1HCRTR2EPHX2 | |
| SCHEMBL9013298 | 0.84 | HCRTR1 (0.33) | NAAACTSKHCRTR1HCRTR2EPHX2 | |
| SCHEMBL8747985 | 0.84 | RARB (0.41) | NAAACTSKFFAR4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676402-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5578244-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |