Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768833 | 0.85 | P2RY6 (0.51) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL1696749 | 0.84 | TDP1 (0.54) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL9420485 | 0.83 | SERPINE1 (0.47) | TDP1CA1CA2TSHRLMNA | |
| SCHEMBL2863947 | 0.80 | ESR1 (0.62) | TSHRLMNACYP1A2CYP2C19ESR1 | |
| SCHEMBL21422382 | 0.80 | TDP1 (0.55) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL26970019 | 0.80 | TDP1 (0.43) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL16351937 | 0.79 | TDP1 (0.50) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL16351931 | 0.79 | TDP1 (0.50) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL7765371 | 0.79 | P2RY6 (0.46) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL21422396 | 0.79 | POLB (0.54) | TDP1POLBAPEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001059455-A2 | IMMOBILIZATION OF BIOACTIVE SPECIES | ACSPURT B.V. (NL) | 2001-08-16 | — | — | WO | disclosed |