Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765371 | 0.86 | P2RY6 (0.46) | P2RY6POLBAPEX1HTTTDP1 | |
| SCHEMBL7770358 | 0.85 | TDP1 (0.45) | P2RY6THRBPOLBAPEX1HTT | |
| SCHEMBL11921516 | 0.83 | THRB (0.55) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22566492 | 0.82 | THRB (0.53) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL27783293 | 0.80 | TSHR (0.42) | P2RY6THRBPOLBAPEX1HTT | |
| SCHEMBL14603427 | 0.79 | PPARA (0.50) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL14028817 | 0.79 | THRB (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10457799 | 0.79 | THRB (0.50) | THRBPOLBAPEX1HTTTDP1 | |
| Hydrochloric Acid SCHEMBL21333307 | 0.78 | P2RY6 (0.49) | P2RY6HSD17B10TP53CYP1A2CYP3A4 | |
| SCHEMBL148322 | 0.78 | SMN1; SMN2 (0.56) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001059455-A2 | IMMOBILIZATION OF BIOACTIVE SPECIES | ACSPURT B.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| WO-2001059455-A2 | IMMOBILIZATION OF BIOACTIVE SPECIES | ACSPURT B.V. (NL) | 2001-08-16 | — | — | WO | disclosed |