Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864212 | 0.87 | TSHR (0.47) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL7768833 | 0.86 | P2RY6 (0.51) | P2RY6HSD17B10POLBAPEX1HTT | |
| SCHEMBL254038 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL7770358 | 0.79 | TDP1 (0.45) | P2RY6HSD17B10ALDH1A1POLBAPEX1 | |
| SCHEMBL7765430 | 0.78 | ELANE (0.51) | P2RY6HSD17B10POLBAPEX1HTT | |
| SCHEMBL10904059 | 0.78 | POLB (0.44) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL19847074 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6374945 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL24019226 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL16125663 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001059455-A2 | IMMOBILIZATION OF BIOACTIVE SPECIES | ACSPURT B.V. (NL) | 2001-08-16 | — | — | WO | claimed |
| WO-2001059455-A2 | IMMOBILIZATION OF BIOACTIVE SPECIES | ACSPURT B.V. (NL) | 2001-08-16 | — | — | WO | disclosed |