Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777642 | 0.83 | PTPN1 (0.44) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL13577697 | 0.83 | KCNK3 (0.45) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL20082202 | 0.70 | PTPN1 (0.44) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL18250665 | 0.69 | PTPN1 (0.43) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL27797782 | 0.66 | RAB9A (0.57) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL5585822 | 0.65 | NPC1 (0.51) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL10427470 | 0.65 | NPC1 (0.47) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL24202631 | 0.64 | SIRT1 (0.83) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| N-Phenylbenzamide SCHEMBL31966 | 0.64 | SIRT1 (0.83) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL126415 | 0.64 | PTPN1 (0.87) | PTPN1KCNK3KCNK9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |