Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452063 | 1.00 | DNM1 (0.41) | DNM1KCNH2SIGMAR1GPR84NPC1 | |
| SCHEMBL8670477 | 1.00 | DNM1 (0.41) | DNM1KCNH2SIGMAR1GPR84NPC1 | |
| SCHEMBL7771807 | 1.00 | DNM1 (0.41) | DNM1KCNH2SIGMAR1GPR84NPC1 | |
| SCHEMBL8664336 | 0.98 | DNM1 (0.38) | DNM1KCNH2SIGMAR1GPR84NPC1 | |
| SCHEMBL2448855 | 0.93 | MAPT (0.37) | KCNH2SIGMAR1ALDH1A1OPRM1 | |
| SCHEMBL4722361 | 0.85 | TP53 (0.33) | KCNH2SIGMAR1DRD3 | |
| SCHEMBL9800560 | 0.84 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL9800595 | 0.84 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL2460597 | 0.84 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL8643073 | 0.84 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| WO-1999039748-A1 | TARGETING IMMUNOREAGENTS USEFUL IN THERAPEUTIC AND DIAGNOSTIC COMPOSITIONS AND METHODS | NYCOMED IMAGING AS (NO) | 1999-08-12 | — | — | WO | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |