Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771807 | 0.98 | DNM1 (0.41) | DNM1KCNH2GPR84SIGMAR1NPC1 | |
| SCHEMBL8670477 | 0.98 | DNM1 (0.41) | DNM1KCNH2GPR84SIGMAR1NPC1 | |
| SCHEMBL7770558 | 0.98 | DNM1 (0.41) | DNM1KCNH2GPR84SIGMAR1NPC1 | |
| SCHEMBL3452063 | 0.98 | DNM1 (0.41) | DNM1KCNH2GPR84SIGMAR1NPC1 | |
| SCHEMBL2448855 | 0.95 | MAPT (0.37) | KCNH2SIGMAR1MAPTOPRM1ALDH1A1 | |
| SCHEMBL4722361 | 0.87 | TP53 (0.33) | KCNH2SIGMAR1DRD3 | |
| SCHEMBL1077660 | 0.84 | KCNH2 (0.38) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL9800560 | 0.82 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL2460597 | 0.82 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 | |
| SCHEMBL8643073 | 0.82 | KCNH2 (0.40) | DNM1KCNH2SIGMAR1NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778828-A | Azolylmethylenehydrazine derivatives and uses thereof | KAKEN PHARMA CO LTD | 2010-07-14 | — | — | CN | disclosed |
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |