Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021516 | 0.89 | FAAH (0.40) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL866506 | 0.86 | KMT2A (0.34) | FAAHKMT2AMEN1CYP1A2SOAT1 | |
| SCHEMBL16640759 | 0.83 | FAAH (0.46) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL19163900 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL12247043 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL13661862 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL16640758 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL16722811 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL18751671 | 0.80 | FAAH (0.48) | FAAHKMT2AMEN1CYP1A2CES1 | |
| SCHEMBL10110819 | 0.79 | CYP1A2 (0.48) | FAAHKMT2AMEN1CYP1A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |