Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29231291 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7765732 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7557327 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7771108 | 0.75 | METAP1 (0.35) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL15368003 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9579117 | 0.71 | DPP4 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9579112 | 0.71 | DPP4 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL27216919 | 0.69 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL12853895 | 0.69 | — | — | |
| SCHEMBL2721800 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |